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Country of origin : India
Simethicone is supplied as an inactive excipient used primarily as an antifoaming and defoaming agent in oral pharmaceutical formulations. It is selected where gas entrapment in suspensions or emulsions may impair product uniformity. For formulation teams, consistent viscosity and droplet size behavior are critical evaluation endpoints. Buyers seeking supply for production batches typically verify COA parameters such as active content and residual solvents where applicable. Packaging options and particle handling recommendations should be matched to manufacturing equipment and scale.
Simethicone is a silicone-based antifoaming agent with low surface tension. It is typically incorporated at low percentage levels to control foaming during production and improve dispensing properties. Compatibility testing with surfactants and emulsifiers is recommended during formulation design. Storage and handling guidance should follow standard excipient practices to retain product performance.
As an antifoam, Simethicone is used in liquid and semi-solid formulations to reduce foam formation during mixing and filling. It aids process robustness by preventing air entrainment and ensuring consistent fill weights. Evaluation focuses on dispersion stability, effect on viscosity, and interaction with surfactant systems. Provide target inclusion rate and intended process stage when requesting technical guidance.
This product is part of our Pharmaceutical Excipients range for formulation buyers.
Request a Simethicone Procurement Quote. Provide target inclusion rate, required pack format, and estimated order volume to get pricing and lead-time. Do not request compositional changes for a standard excipient SKU.